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1

Final Validation of the ProMisE Molecular Classifier for Endometrial Carcinoma in a Large Population-based Case Series.

Kommoss, S, McConechy, M K, Kommoss, F, Leung, S, Bunz, A, Magrill, J, Britton, H, Kommoss, F, Grevenkamp, F, Karnezis, A, Yang, W, Lum, A, Krämer, B, Taran, F, Staebler, A, Lax, S, Brucker, S Y, Hunt

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 697 KB

english, 2018

2

Interobserver Agreement in Endometrial Carcinoma Histotype Diagnosis Varies Depending on The Cancer Genome Atlas (TCGA)-based Molecular Subgroup

Hoang, Lien N., Kinloch, Mary A., Leo, Joyce M., Grondin, Katherine, Lee, Cheng-Han, Ewanowich, Carol, Köbel, Martin, Cheng, Angela, Talhouk, Aline, McConechy, Melissa, Huntsman, David G., McAlpine, J

Journal:

American Journal of Surgical Pathology

Year:

2017

Language:

english

File:

PDF, 825 KB

english, 2017

3

Molecular Classification of Grade 3 Endometrioid Endometrial Cancers Identifies Distinct Prognostic Subgroups

Bosse, Tjalling, Nout, Remi A., McAlpine, Jessica N., McConechy, Melissa K., Britton, Heidi, Hussein, Yaser R., Gonzalez, Carlene, Ganesan, Raji, Steele, Jane C., Harrison, Beth T., Oliva, Esther, Vid

Journal:

American Journal of Surgical Pathology

Year:

2018

Language:

english

File:

PDF, 490 KB

english, 2018

4

Histotype-Genotype Correlation in 36 High-grade Endometrial Carcinomas

Hoang, Lien N., McConechy, Melissa K., Köbel, Martin, Han, Guangming, Rouzbahman, Marjan, Davidson, Ben, Irving, Julie, Ali, Rola H., Leung, Sam, McAlpine, Jessica N., Oliva, Esther, Nucci, Marisa R.,

Journal:

American Journal of Surgical Pathology

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

5

Auroral Displays at Saskatoon

PETRIE, W., FORSYTH, P. A., MCCONECHY, E.

Journal:

Year:

1949

File:

PDF, 264 KB

1949

6

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas

Tone, Alicia A, McConechy, Melissa K, Yang, Winnie, Ding, Jiarui, Yip, Stephen, Kong, Esther, Wong, Kwong-Kwok, Gershenson, David M, Mackay, Helen, Shah, Sohrab, Gilks, Blake, Tinker, Anna V, Clarke,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

7

Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma

Hoang, Lien N., McConechy, Melissa K., Köbel, Martin, Anglesio, Michael, Senz, Janine, Maassen, Malden, Kommoss, Stefan, Meng, Bo, Postovit, Lynne, Kelemen, Linda E., Staebler, Annette, Brucker, Sara,

Journal:

International Journal of Gynecological Cancer

Year:

2015

Language:

english

File:

PDF, 1.54 MB

english, 2015

8

Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer

Talhouk, Aline, McConechy, Melissa K., Leung, Samuel, Yang, Winnie, Lum, Amy, Senz, Janine, Boyd, Niki, Pike, Judith, Anglesio, Michael, Kwon, Janice S., Karnezis, Anthony N., Huntsman, David G., Gilk

Journal:

Year:

2017

Language:

english

File:

PDF, 378 KB

english, 2017

9

STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer

Kharma, B., Baba, T., Matsumura, N., Kang, H. S., Hamanishi, J., Murakami, R., McConechy, M. M., Leung, S., Yamaguchi, K., Hosoe, Y., Yoshioka, Y., Murphy, S. K., Mandai, M., Hunstman, D. G., Konishi,

Journal:

Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

10

Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype

McConechy, Melissa K., Färkkilä, Anniina, Horlings, Hugo M., Talhouk, Aline, Unkila-Kallio, Leila, van Meurs, Hannah S., Yang, Winnie, Rozenberg, Nirit, Andersson, Noora, Zaby, Katharina, Bryk, Saara,

Journal:

JNCI Journal of the National Cancer Institute

Year:

2016

Language:

english

File:

PDF, 794 KB

english, 2016

11

LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers

Xia, Zhouchunyang, Cochrane, Dawn R., Anglesio, Michael S., Wang, Yi Kan, Nazeran, Tayyebeh, Tessier-Cloutier, Basile, McConechy, Melissa K., Senz, Janine, Lum, Amy, Bashashati, Ali, Shah, Sohrab P.,

Journal:

Gynecologic Oncology

Year:

2017

Language:

english

File:

PDF, 691 KB

english, 2017

12

Interpretation of somatic POLE mutations in endometrial carcinoma

León‐Castillo, Alicia, Britton, Heidi, McConechy, Melissa K., McAlpine, Jessica N., Nout, Remi, Kommoss, Stefan, Brucker, Sara Y., Carlson, Joseph W., Epstein, Elisabeth, Rau, Tilman, Bosse, Tjalling,

Journal:

The Journal of Pathology

Year:

2019

File:

PDF, 2.61 MB

2019

13

Histopathological features of endometrial carcinomas associated with POLE mutations: implications for decisions about adjuvant therapy

Bakhsh, Salwa, Kinloch, Mary, Hoang, Lien N., Soslow, Robert, Köbel, Martin, Lee, Cheng-Han, McAlpine, Jessica N., McConechy, Melissa K., Gilks, C Blake

Journal:

Year:

2015

File:

PDF, 244 KB

2015

14

Systematic analysis of somatic mutations impacting gene expression in 12 tumour types

J. Ding, M. K. Mcconechy, H. M. Horlings, G. Ha, F. Chun Chan, T. Funnell, S. C. Mullaly, J. Reimand, A. Bashashati, G. D. Bader, D. Huntsman, S. Aparicio, A. Condon, S. P. Shah

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

15

Clinicopathological and molecular characterisation of “multiple classifier” endometrial carcinomas

León‐Castillo, Alicia, Gilvazquez, Ester, Nout, Remi, Smit, Vincent T.H.B.M., McAlpine, Jessica N., McConechy, Melissa, Kommoss, Stefan, Brucker, Sara Y., Carlson, Joseph W., Epstein, Elisabeth, Rau,

Journal:

The Journal of Pathology

Year:

2019

File:

PDF, 3.41 MB

2019

16

Optimizing molecular residual disease detection using liquid biopsy postoperatively in early stage lung cancer

McGuire, Anna L, Hughesman, Curtis B, McConechy, Melissa K, Melosky, Barb, Lam, Stephen, Myers, Renelle, Yee, John, Tang, Ernest, Yip, Stephen

Journal:

Lung Cancer Management

Year:

2020

File:

PDF, 537 KB

2020

17

Steroid Hormone Control of Cell Death and Cell Survival: Molecular Insights Using RNAi

Chittaranjan, Suganthi, McConechy, Melissa, Hou, Ying-Chen Claire, Freeman, J. Douglas, DeVorkin, Lindsay, Gorski, Sharon M., Rulifson, Eric

Journal:

Year:

2009

Language:

english

File:

PDF, 1.28 MB

english, 2009

18

FOXL2 402C>G Mutation Can Be Identified in the Circulating Tumor DNA of Patients with Adult Granulosa Cell Tumors

Färkkilä, Anniina, McConechy, Melissa K., Yang, Winnie, Talhouk, Aline, Ng, Ying, Lum, Amy, Morin, Ryan D., Bushell, Kevin, Riska, Annika, McAlpine, Jessica N., Gilks, C. Blake, Unkila-Kallio, Leila,

Journal:

The Journal of Molecular Diagnostics

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

19

Detection of DNA mismatch repair (MMR) deficiencies by immunohistochemistry can effectively diagnose the microsatellite instability (MSI) phenotype in endometrial carcinomas

McConechy, M.K., Talhouk, A., Li-Chang, H.H., Leung, S., Huntsman, D.G., Gilks, C.B., McAlpine, J.N.

Journal:

Gynecologic Oncology

Year:

2015

Language:

english

File:

PDF, 262 KB

english, 2015

20

ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas

Wiegand, Kimberly C., Shah, Sohrab P., Al-Agha, Osama M., Zhao, Yongjun, Tse, Kane, Zeng, Thomas, Senz, Janine, McConechy, Melissa K., Anglesio, Michael S., Kalloger, Steve E., Yang, Winnie, Heravi-Mo

Journal:

Boston Medical and Surgical Journal

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010

21

Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary

Färkkilä, Anniina, Haltia, Ulla-Maija, Tapper, Johanna, McConechy, Melissa K., Huntsman, David G., Heikinheimo, Markku

Journal:

Annals of Medicine

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

22

Immunohistochemical characterization of prototypical endometrial clear cell carcinoma-diagnostic utility of HNF-1β and oestrogen receptor

Hoang, Lien N, Han, Guangming, McConechy, Melissa, Lau, Sherman, Chow, Christine, Gilks, C Blake, Huntsman, David G, Köbel, Martin, Lee, Cheng-Han

Journal:

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

23

Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research

Hughes, Christopher S., McConechy, Melissa K., Cochrane, Dawn R., Nazeran, Tayyebeh, Karnezis, Anthony N., Huntsman, David G., Morin, Gregg B.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.93 MB

english, 2016

24

Major p53 immunohistochemical patterns in in situ and invasive squamous cell carcinomas of the vulva and correlation with TP53 mutation status

Tessier-Cloutier, Basile, Kortekaas, Kim E., Thompson, Emily, Pors, Jennifer, Chen, Julia, Ho, Julie, Prentice, Leah M., McConechy, Melissa K., Chow, Christine, Proctor, Lily, McAlpine, Jessica N., Hu

Journal:

Modern Pathology

Year:

2020

File:

PDF, 8.96 MB

2020

25

Use of mutation profiles to refine the classification of endometrial carcinomas

Melissa K McConechy, Jiarui Ding, Maggie CU Cheang, Kimberly C Wiegand, Janine Senz, Alicia A Tone, Winnie Yang, Leah M Prentice, Kane Tse, Thomas Zeng, Helen McDonald, Amy P Schmidt, David G Mutch, J

Journal:

The Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 3.32 MB

english, 2012

26

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] A15. GENOMICS IN CRITICAL CARE: A COMING OF AGE - The GG Genotype Of Angiotensin II Type 1 Receptor-Associated Protein Gene Rs11121816 Polymorphism Is Associated With Increased Mortality In Septic Shock

Nakada, Taka-aki, Russell, James A., Boyd, John H., McLaughlin, Luke, Nakada, Emiri, Thair, Simone A., McConechy, Melissa, Thain, Katherine R., Aguirre-Hernandez, Rosalia, Walley, Keith R.

Year:

2010

Language:

english

File:

PDF, 17 KB

english, 2010

27

Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

Salloum, Ralph, McConechy, Melissa K., Mikael, Leonie G., Fuller, Christine, Drissi, Rachid, DeWire, Mariko, Nikbakht, Hamid, De Jay, Nicolas, Yang, Xiaodan, Boue, Daniel, Chow, Lionel M. L., Finlay,

Journal:

Acta Neuropathologica Communications

Year:

2017

Language:

english

File:

PDF, 3.25 MB

english, 2017

28

Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas

Melissa K McConechy, Michael S Anglesio, Steve E Kalloger, Winnie Yang, Janine Senz, Christine Chow, Alireza Heravi-Moussavi, Gregg B Morin, Anne-Marie Mes-Masson, Australian Ovarian Cancer Study Grou

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 194 KB

english, 2011

29

Endometrial carcinomas with POLE exonuclease domain mutations have a favorable prognosis

McConechy, M. K., Talhouk, A., Leung, S., Chiu, D. S., Yang, W., Senz, J., Reha-Krantz, L. J., Lee, C.-H., Huntsman, D. G., Gilks, B., McAlpine, J. N.

Journal:

Clinical Cancer Research

Year:

2016

Language:

english

File:

PDF, 463 KB

english, 2016

30

NIH Public Access

Mcconechy, Melissa K, Ding, Jiarui, Cheang, Maggie C U, Wiegand, Kimberly, Tone, Alicia, Yang, Winnie, Prentice, Leah, Tse, Kane, Zeng, Thomas, Schmidt, Amy P, Mutch, David G, Mcalpine, Jessica N, Hir

Year:

2014

Language:

english

File:

PDF, 812 KB

english, 2014

31

Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: Earlier prognostic information to guide treatment

Talhouk, Aline, Hoang, Lien N., McConechy, Melissa K., Nakonechny, Quentin, Leo, Joyce, Cheng, Angela, Leung, Samuel, Yang, Winnie, Lum, Amy, Köbel, Martin, Lee, Cheng-Han, Soslow, Robert A., Huntsman

Journal:

Gynecologic Oncology

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

32

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

Bashashati, Ali, Ha, Gavin, Tone, Alicia, Ding, Jiarui, Prentice, Leah M, Roth, Andrew, Rosner, Jamie, Shumansky, Karey, Kalloger, Steve, Senz, Janine, Yang, Winnie, McConechy, Melissa, Melnyk, Natali

Journal:

The Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 2.09 MB

english, 2013

33

Methylome analysis and whole-exome sequencing reveal that brain tumors associated with encephalocraniocutaneous lipomatosis are midline pilocytic astrocytomas

Valera, Elvis Terci, McConechy, Melissa K., Gayden, Tenzin, Rivera, Barbara, Jones, David T. W., Wittmann, Andrea, Han, HyeRim, Bareke, Eric, Nikbakht, Hamid, Mikael, Leonie, Queiroz, Rosane Gomes, Su

Journal:

Acta Neuropathologica

Year:

2018

Language:

english

File:

PDF, 976 KB

english, 2018

34

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, S

Journal:

Year:

2019

Language:

english

File:

PDF, 849 KB

english, 2019

35

In-depth molecular profiling of the biphasic components of uterine carcinosarcomas

McConechy, Melissa K, Hoang, Lien N, Chui, Michael Herman, Senz, Janine, Yang, Winnie, Rozenberg, Nirit, Mackenzie, Robertson, McAlpine, Jessica N, Huntsman, David G, Clarke, Blaise A, Gilks, Cyril Bl

Journal:

The Journal of Pathology Clinical Research

Year:

2015

Language:

english

File:

PDF, 946 KB

english, 2015

36

Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles

McConechy, Melissa K, Ding, Jiarui, Senz, Janine, Yang, Winnie, Melnyk, Nataliya, Tone, Alicia A, Prentice, Leah M, Wiegand, Kimberly C, McAlpine, Jessica N, Shah, Sohrab P, Lee, Cheng-Han, Goodfellow

Journal:

Modern Pathology

Year:

2014

Language:

english

File:

PDF, 678 KB

english, 2014

37

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, S

Journal:

Year:

2019

Language:

english

File:

PDF, 4.60 MB

english, 2019

38

β 2 -Adrenergic Receptor Gene Polymorphism Is Associated with Mortality in Septic Shock

Nakada, Taka-aki, Russell, James A., Boyd, John H., Aguirre-Hernandez, Rosalia, Thain, Katherine R., Thair, Simone A., Nakada, Emiri, McConechy, Melissa, Walley, Keith R.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

39

HGG-06. CHARACTERIZING TEMPORAL GENOMIC HETEROGENEITY IN PEDIATRIC HIGH-GRADE GLIOMAS

Salloum, Ralph, McConechy, Melissa K., Mikael, Leonie G., Nikhbakht, Hamid, De Jay, Nicolas, Fuller, Christine, Drissi, Rachid, DeWire, Mariko, Boue, Daniel R, Chow, Lionel, Gayden, Tenzin, Karamchand

Journal:

Year:

2017

Language:

english

File:

PDF, 82 KB

english, 2017

40

Molecular characterization of invasive and in situ squamous neoplasia of the vulva and implications for morphologic diagnosis and outcome

Tessier-Cloutier, Basile, Pors, Jennifer, Thompson, Emily, Ho, Julie, Prentice, Leah, McConechy, Melissa, Aguirre-Hernandez, Rosalia, Miller, Ruth, Leung, Samuel, Proctor, Lily, McAlpine, Jessica N.,

Journal:

Modern Pathology

Year:

2020

File:

PDF, 2.65 MB

2020

41

[BMJ Publishing Group Ltd IGCS Annual 2019 Meeting Abstracts - ()] Regional plenary - 49âCirculating cell-free tumour dna for surveillance of endometrial and ovarian carcinoma

Lum, A, Lam, S, Nazeran, M, Yang, W, Senz, J, Hernandez, R, Malikic, S, McConechy, M, Huntsman, DG, McAlpine, J

File:

PDF, 61 KB

42

A Single Nucleotide Polymorphism in NF- B Inducing Kinase Is Associated with Mortality in Septic Shock

Thair, S. A., Walley, K. R., Nakada, T.-a., McConechy, M. K., Boyd, J. H., Wellman, H., Russell, J. A.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 343 KB

english, 2011

43

Histopathological features of endometrial carcinomas associated with POLE mutations: implications for decisions about adjuvant therapy

Bakhsh, Salwa, Kinloch, Mary, Hoang, Lien N., Soslow, Robert, Köbel, Martin, Lee, Cheng-Han, McAlpine, Jessica N., McConechy, Melissa K., Gilks, C Blake

Journal:

Year:

2015

Language:

english

File:

PDF, 244 KB

english, 2015

44

Evaluation of endometrial carcinoma prognostic immunohistochemistry markers in the context of molecular classification

Karnezis, Anthony N, Leung, Samuel, Magrill, Jamie, McConechy, Melissa K, Yang, Winnie, Chow, Christine, Kobel, Martin, Lee, Cheng-Han, Huntsman, David G, Talhouk, Aline, Kommoss, Friederich, Gilks, C

Journal:

The Journal of Pathology Clinical Research

Year:

2017

Language:

english

File:

PDF, 638 KB

english, 2017

45

mRNA induces RANTES production in trophoblast cells via TLR3 only when delivered intracellularly using lipid membrane encapsulation

E. Nakada, T.A. Nakada, K.R. Walley, M. McConechy, L. McLaughlin, P. von Dadelszen, M. Shozu, J.H. Boyd

Journal:

Year:

2011

Language:

english

File:

PDF, 462 KB

english, 2011

46

A clinically applicable molecular-based classification for endometrial cancers

Talhouk, A, McConechy, M K, Leung, S, Li-Chang, H H, Kwon, J S, Melnyk, N, Yang, W, Senz, J, Boyd, N, Karnezis, A N, Huntsman, D G, Gilks, C B, McAlpine, J N

Journal:

British Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

47

Acute organ injury is associated with alterations in the cell-free plasma transcriptome

Boyd, John H, McConechy, Melissa, Walley, Keith R

Journal:

Intensive Care Medicine Experimental

Year:

2014

Language:

english

File:

PDF, 517 KB

english, 2014

48

VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock

Nakada, Taka-aki, Boyd, John H., Russell, James A., Aguirre-Hern�ndez, Rosal�a, Wilkinson, Mark D., Thair, Simone A., Nakada, Emiri, McConechy, Melissa K., Fjell, Christopher D., Walley, Keith R.

Journal:

Journal of Innate Immunity

Year:

2015

Language:

english

File:

PDF, 659 KB

english, 2015

49

Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice

Toonchai Indrambarya,John H Boyd,Yingjin Wang,Melissa McConechy…

Journal:

Critical Care (BioMed Central)

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

50

Targeted mutation analysis of endometrial clear cell carcinoma

Hoang, Lien N, McConechy, Melissa K, Meng, Bo, McIntyre, John B, Ewanowich, Carol, Gilks, Cyril Blake, Huntsman, David G, Köbel, Martin, Lee, Cheng-Han

Journal:

Year:

2015

Language:

english

File:

PDF, 2.20 MB

english, 2015

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